Hi Donna,
My wife has been treated for depression since 1986, her situation is complicated by a body that is hypersensitive to drugs. We too were running out of options around this time last year when her psyc suggested we research VNS; to make a long story short, we decided to try it and she was implanted in April 2005.
Contrary to what we read, we began to notice major improvement in just a few weeks, and nearly medication free by August, the device has been a complete turn-around for her.
It has not been completely withou issues-- we still have regular visits with her doctor to make treatment adjustments-- but life has not been this stable in 20 years.
An example from her perspective: I was away on family business during October when she had an issue with stimulation-- though attached to the Left vagus nerve, it began cross-stimulating her Right vagus nerve and causing painfull stomach spasms (since eliminated by reprogramming). When her doctor asked why she waited sooo long to call, she said that she was afraid he would turn it off!
She just walked by and asked me who I was writing to... and said in her opinion it has been an absolutely positive experience, it just takes time to get everything adjusted.
I hope you find relief,
mg